ABSTRACT
Abstract Background Nipple eczema is a less common presentation of atopic dermatitis. No studies in the literature have correlated nipple eczema in pregnancy as a manifestation of atopic dermatitis. Objective To evaluate whether nipple eczema presenting in pregnancy is a manifestation of atopic dermatitis. Methods This was a prospective observational study including 100 women who presented with nipple eczema for the first time during pregnancy. The exclusion criteria were any patient with previous history of nipple eczema, those already on oral or topical treatment for atopic dermatitis or nipple eczema, and other disorders mimicking eczema. Patients were divided into two groups ‒ nipple eczema with atopic dermatitis and without atopic dermatitis. Demographic data, clinical features, total leukocyte count, differential leukocyte count, absolute eosinophil counts, and serum IgE levels were compared between the two groups to detect association between nipple eczema in pregnancy and atopic dermatitis. Results Out of 100 patients, 39 were diagnosed with atopic dermatitis, whereas 61 were ruled out to have any features suggestive of atopic dermatitis. There were no statistically significant differences in mean age, mean duration of symptoms, and serum IgE levels. In patients with atopic dermatitis, bilateral symptoms were noted more commonly than in patients without the disease, but this was statistically insignificant. Study limitations Lack of long term follow-up and no large studies in literature to compare results. Conclusion Nipple eczema in pregnancy follows a similar pattern as in other age groups. The clinical profile of patients is similar in cases with and without atopic dermatitis.
Subject(s)
Humans , Female , Pregnancy , Adult , Breast Diseases/pathology , Dermatitis, Atopic/pathology , Eczema/pathology , Nipples/pathology , Pregnancy Complications/pathology , Breast Diseases/diagnosis , Breast Diseases/blood , Immunoglobulin E/blood , Prospective Studies , Dermatitis, Atopic/diagnosis , Dermatitis, Atopic/blood , Eczema/diagnosis , Eczema/blood , India , Leukocyte Count , NeutrophilsABSTRACT
La dermatitis o eccema numular es una patología poco frecuente en pediatría. El cuadro se caracteriza por un inicio con diminutas pápulas y vesículas eritematovioláceas que confluyen en placas exudativas de forma circular y evolucionan a placas eccematosas o liquenificadas de forma discoide o anular. Aparecen, predominantemente, en superficies extensoras de las extremidades, aunque pueden encontrarse en el tronco, las manos o los pies. El diagnóstico es clínico; solo en casos con mala evolución pueden ser necesarias pruebas complementarias. La base del tratamiento son los corticoides tópicos y, si se encuentra un desencadenante infeccioso, el tratamiento de la causa. Su evolución suele ser crónica o recidivante. Se presentan dos casos clínicos en población pediátrica con la finalidad de difundir entre los pediatras su conocimiento y manejo.
Nummular eczema or dermatitis is an uncommon paediatric pathology. It is presented as red-purplish small papules and vesicles that join to form exudative circular patches and then to eczematous or lichenified patches with discoid shape. The lesions appear predominantly on the extensor surface of extremities, although they can appear in trunk, hands or feet. This pathology has a clinical diagnosis; only few cases require complementary test. The topical corticosteroids are the mainstay of the treatment, and the causal treatment whether an infectious trigger is found. The patients have chronic or recurrent evolution. We report two cases in children with the aim of spreading knowledge among pediatricians.
Subject(s)
Humans , Male , Female , Infant , Child, Preschool , Dermatitis/pathology , Dermatitis/therapy , Eczema/pathology , Eczema/therapySubject(s)
Female , Pregnancy , Foodborne Diseases/complications , Hypersensitivity, Immediate/blood , Food Hypersensitivity/etiology , Egg Hypersensitivity/metabolism , Immunochemistry/methods , Shellfish/toxicity , Dietary Proteins/administration & dosage , Anaphylaxis/etiology , Asthma/pathology , Egg White/adverse effects , Eczema/pathologyABSTRACT
Tinea incognito (TI) is a dermatophytic infection which has lost its typical clinical appearance because of improper use of steroids or calcineurin inhibitors. The incidence of TI is increasing nowadays. We conducted retrospective review on 283 patients with TI from 25 dermatology training hospitals in Korea from 2002-2010 to investigate the demographical, clinical, and mycological characteristics of TI, and to determine the associated risk factors. More than half (59.3%) patients were previously treated by non-dermatologists or self-treated. The mean duration of TI was 15.0 +/- 25.3 months. The most common clinical manifestations were eczema-like lesion, psoriasis-like, and lupus erythematosus-like lesion. The trunk and face were frequently involved, and 91 patients (32.2%) also had coexisting fungal infections. Among 67 isolated strains, Trichophyton rubrum was the most frequently detected (73.1%). This is the largest study of TI reported to date and the first investigational report concerning TI in Korea. We suggest that doctors should consider TI when a patient has intractable eczema-like lesions accompanied by tinea pedis/unguium. Furthermore, there should be a policy change, which would make over-the-counter high-potency topical steroids less accessible in some countries, including Korea.
Subject(s)
Adolescent , Adult , Aged , Aged, 80 and over , Child , Child, Preschool , Female , Humans , Male , Middle Aged , Young Adult , Demography , Eczema/pathology , Face/pathology , Lupus Erythematosus, Cutaneous/pathology , Psoriasis/pathology , Republic of Korea , Retrospective Studies , Risk Factors , Tinea/diagnosis , Trichophyton/isolation & purificationABSTRACT
A one year study, from March, 1987 to February, 1988, was conducted on 4124 skin only patients in the only paediatric hospital, Dhaka, Bangladesh to show the distribution of different types of skin deseases in children. The types of skin infections were catagorised into five different groups as bacterial scabies, infected scabies, eczema and dermatitis, fundal and miscellaneous. The range of the ages of the studied patients in the presentation was from 0-15 years. In this study, 2176 [53%] patients were male whereas the rest 1940 [47%] were females. In all the cases, the number of male patients were found to be higher than females except in bacterial infection where 64.8% were between the age of 0 - 5 years while 9-10 years age group had 24.4% cases and 11-15 year age group, 10.8%
Subject(s)
Humans , Child , Eczema/etiology , Eczema/pathology , /etiology , Scabies/complicationsABSTRACT
Se presenta una lactante de 16 años de edad con un eczema perinévico o halo eczema que se desarrolló alrededor de un nevo melanocítico congénito. La dermatosis inflamatoria se inició dos meses antes. El nevo era máculo-papuloso, negro, de 5mm, y con límites mal definidos e irregulares, correspondiendo a una proliferación melanocítica juntural intraepidérmica. La histopatología del area del eczema mostró una dermatitis espongiótica con escasos queratinocitos necrobiótico. Sugerimos que estas imágenes puedan corresponder a dos mecanismos fisiopatológicos inmunes de hipersensibilidad retardada y de citotoxicidad mediados por linfocitos T, desencadenados por la liberación de neoantígenos del nevo. El eczema mejoró espontáneamente en el término de tres meses. El nevo melanocítico permaneció con iguales características